Strategic Timing of Anti-Retroviral Treatment (START Study)

Project Timeline

2016 – Now

The START trial was designed to address the question: In HIV-1 (subsequently referred to as HIV) infected asymptomatic participants with a CD4+ count greater than 500 cells/mm3, is immediate use of antiretroviral therapy (ART) superior to deferral of ART until the CD4+ count declines to 350 cells/mm3 or AIDS develops in terms of morbidity and mortality? The study is being conducted at 237 sites in 35 countries. Global enrolment closed with 4,688 participants enrolled.

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Other Current Projects

WHO: Strengthening Civil Society Engagement in the COVID-19 Response at the National and Local Levels - Vaccination, Decarceration and Community Reintegration of People in Prison amidst COVID-19 in Malaysia
An Open-label, Randomized, Adaptive Cross-over Interventional Study to Evaluate the Efficacy of Tocilizumab versus Corticosteroids in hospitalised COVID-19 patients with high risk of progression (STORM Study)
National Health and Medical Research: Towards a functional cure for Hepatitis B Virus: exploiting lessons from HBV-HIV co-infection (COMMIT Study)