Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is a serious infection that can result in significant morbidity and mortality. A retrospective cohort study was conducted to determine the predictors of mortality in patient with MRSA bacteremia correlating with clinical, phenotypic and genotypic…
It has been estimated that there are 170,000 people who inject drugs (PWID) in Malaysia. HIV prevalence among PWID in Malaysia ranges from 25 % to 45 %. Further, people who inject drugs (PWID) account for 39 % of all…
Community Action on Harm Reduction project, implemented by the Alliance with support of the Ministry of Foreign Affairs of the government of the Netherlands (as a project number 23389), started on 1 January, 2011. The project involves work in five…
A case documentation on good practice values of civil society organisations (CSOs) in HIV response was carried out by the Malaysian AIDS Council (MAC), with the aim to showcase how CSOs that have been traditionally depending on the Ministry of…
Compulsory drug detention centers (CDDCs) are common throughout Asia. However, medical treatments for substance use disorders, such as opioid agonist treatment (OAT), are generally unavailable in these settings. In this report, we compare the effectiveness of CDDCs with voluntary drug…
Antiretroviral therapy is complicated by drug interactions and contraindications. Novel regimens are needed. This open label study randomly assigned treatment-naive, human immunodeficiency virus (HIV)—infected subjects to receive tenofovir-emtricitabine with efavirenz (Arm I), with ritonavir-boosted atazanavir (Arm II), or with zidovudine/abacavir…
WHO-recommended second-line antiretroviral therapy (ART) of a pharmacologically enhanced (boosted) protease inhibitor plus nucleoside or nucleotide reverse transcriptase inhibitors (NtRTIs) might be compromised by resistance. Results of the 96 week SECOND-LINE randomised trial showed that NtRTI-sparing ART with ritonavir-boosted lopinavir…
“ENCORE (for Evaluation of Novel Concepts in Optimization of antiRetroviral Efficacy) was a program originally designed to examine the safety and efficacy of lower doses of important antiretroviral drugs (ART). This was intended to allow donors, governments and non-government organisations…
